The Zen of Python, by Tim Peters has been adopted by many as a model summary manual of python's philosophy.  Though these statements should be considered more as guideline and not mandatory rules, developers worldwide find the poem to be on a solid guiding ground.

Beautiful is better than ugly.
Explicit is better than implicit.
Simple is better than complex.
Complex is better than complicated.
Flat is better than nested.
Sparse is better than dense.
Readability counts.
Special cases aren't special enough to break the rules.
Although practicality beats purity.
Errors should never pass silently.
Unless explicitly silenced.
In the face of ambiguity, refuse the temptation to guess.
There should be one-- and preferably only one --obvious way to do it.
Although that way may not be obvious at first unless you're Dutch.
Now is better than never.
Although never is often better than *right* now.
If the implementation is hard to explain, it's a bad idea.
If the implementation is easy to explain, it may be a good idea.
Namespaces are one honking great idea -- let's do more of those!

Python is an incredibly powerful and useful computer programming language that many of the biggest websites in the world rely on for their foundation. Python provides reliable results that are functional and involve a variety of dynamic scripted and non-scripted contexts. And because it is free and open source, it has remained a popular choice for a variety of different developers who are looking to build new sites on one of the most reliable languages available. Here is a look at 10 of the most famous software programs that are written in Python and what they do.

YouTube
If you love watching hours of homemade and professional quality video clips on YouTube, you can thank Python for giving you that option. The foundation for Python helped YouTube integrate streaming videos into their pages, as well as the ability to like videos and embed certain information. YouTube is one of the most popular sites on the Internet, and it runs off of one of the most powerful languages in Python.

DropBox
What started as a powerful app, DropBox is now used by a variety of individuals, businesses, companies, organizations and more. This program lets you save files to a cloud-based service, that you can then access from anywhere in the world. With Python at the root of DropBox, there is no longer a need for USB sticks or blank CDs, since you can now save and share everything with your cloud-based account.

Google
It takes a lot of power to be able to handle the most popular search engine in the entire world. That is why Google uses Python for its mainframe foundation, as well as in addition to various apps that it runs in conjunction with the main site. The ease that Google provides for finding certain information, would be impossible without Python at the core.

Quora
Got a question? Ask it on Quora. This site compiles a list of questions and answers that come from a community of individuals. Those questions are then organized by various members of the community, which puts the most relevant information at the top. The creators of Quora, who happened to be former Facebook employees, decided to use Python to help them create the world’s best Magic 8 ball in Quora.

Instagram
If you love taking photos of your food or a new outfit and posting it online for all of your friends to see, you can thank Python for that ability. Granted, Instagram has both a very powerful app and a website, but the latter runs on Python language. The system allows for users to browse, find and post pictures that they like on the site.

BitTorrent
BitTorrent has evolved quite a bit in recent years, but its foundation and earlier years were built on Python. When it comes to one of the largest databases of knowledge, media and content, BitTorrent is the way to go. But you wouldn’t be able to get any of those lectures or other legal stuff that you are downloading from BitTorrent, if it wasn’t for Python.

Spotify
Spotify changed the music game when it allowed you to listen to ad-free music of your choice. This wasn’t a program where you got to select a playlist, but rather full songs that you love, on repeat as many times as you can imagine, if you so desire. But whether you are rocking out to the latest K-Pop song from Psy or a classic jazz tune, you are doing so because Spotify was built on Python.

Reddit
Reddit is one of the biggest open communities on the web. You have a question, want to talk about something in specific, or find tons of information regarding a particular topic, you can just look on Reddit. The site relies on Python to help them store user names, categorize subreddits, upload links to GIFs and, of course, award gold to valued posters.

Yahoo Maps
Much like Google, Yahoo also uses Python for a variety of different resources. Most valued may be Yahoo Maps. The API and programming behind the maps program, which is built with Python, allows for users to find locations, get directions and even find reviews about local places.

Hipmunk
If you love to travel, you have likely come across Hipmunk. And while the site lets you save money on booking your itinerary through Hipmunk, it is Python that keeps everything organized. Python also helps sort the best discounts and rates, so you can get the best packages available.

Python is an incredibly powerful tool for web development. More and more sites rely on it, including 10 of the most powerful sites in the world that are listed here.

Related:

Current Active List of Organizations that use Python 

Working With Lists In Python

When making a strategic cloud decision, organizations can follow either one of two ideologies: open or closed.

In the past, major software technologies have been widely accepted because an emerging market leader simplified the initial adoption.  After a technology comes of age, the industry spawns open alternatives that provide choice and flexibility, and the result is an open alternative that quickly gains traction and most often outstrips the capabilities of its proprietary predecessor.

After an organization invests significantly in a technology, the complexity and effort required steering a given workload onto a new system or platform is, in most cases, significant. Switching outlays, shifting to updated or new software/hardware platforms, and the accompanying risks may lead to the ubiquitousness of large, monolithic and complex ERP systems – reason not being that they offer the best value for an organization, but rather because shifting to anything else is simply – unthinkable.

There’s no denying that these are critical considerations today since a substantial number of organizations are making their first jump into the cloud and making preparations for the upsetting shift in how IT is delivered to both internal and external clientele. Early adopters are aware of the fact that the innovation brought about by open technologies can bring dramatic change, and hence are realizing how crucial it is to be able to chart their own destiny.

Checking to see if a file exists is a two step process in Python. Simply import the module shown below and invoke the isfile function:

import os.path
os.path.isfile(fname)