The Zen of Python, by Tim Peters has been adopted by many as a model summary manual of python's philosophy.  Though these statements should be considered more as guideline and not mandatory rules, developers worldwide find the poem to be on a solid guiding ground.

Beautiful is better than ugly.
Explicit is better than implicit.
Simple is better than complex.
Complex is better than complicated.
Flat is better than nested.
Sparse is better than dense.
Readability counts.
Special cases aren't special enough to break the rules.
Although practicality beats purity.
Errors should never pass silently.
Unless explicitly silenced.
In the face of ambiguity, refuse the temptation to guess.
There should be one-- and preferably only one --obvious way to do it.
Although that way may not be obvious at first unless you're Dutch.
Now is better than never.
Although never is often better than *right* now.
If the implementation is hard to explain, it's a bad idea.
If the implementation is easy to explain, it may be a good idea.
Namespaces are one honking great idea -- let's do more of those!

It is said that spoken languages shape thoughts by their inclusion and exclusion of concepts, and by structuring them in different ways. Similarly, programming languages shape solutions by making some tasks easier and others less aesthetic. Using F# instead of C# reshapes software projects in ways that prefer certain development styles and outcomes, changing what is possible and how it is achieved.

F# is a functional language from Microsoft's research division. While once relegated to the land of impractical academia, the principles espoused by functional programming are beginning to garner mainstream appeal.

As its name implies, functions are first-class citizens in functional programming. Blocks of code can be stored in variables, passed to other functions, and infinitely composed into higher-order functions, encouraging cleaner abstractions and easier testing. While it has long been possible to store and pass code, F#'s clean syntax for higher-order functions encourages them as a solution to any problem seeking an abstraction.

F# also encourages immutability. Instead of maintaining state in variables, functional programming with F# models programs as a series of functions converting inputs to outputs. While this introduces complications for those used to imperative styles, the benefits of immutability mesh well with many current developments best practices.

For instance, if functions are pure, handling only immutable data and exhibiting no side effects, then testing is vastly simplified. It is very easy to test that a specific block of code always returns the same value given the same inputs, and by modeling code as a series of immutable functions, it becomes possible to gain a deep and highly precise set of guarantees that software will behave exactly as written.

Further, if execution flow is exclusively a matter of routing function inputs to outputs, then concurrency is vastly simplified. By shifting away from mutable state to immutable functions, the need for locks and semaphores is vastly reduced if not entirely eliminated, and multi-processor development is almost effortless in many cases.

Type inference is another powerful feature of many functional languages. It is often unnecessary to specify argument and return types, since any modern compiler can infer them automatically. F# brings this feature to most areas of the language, making F# feel less like a statically-typed language and more like Ruby or Python. F# also eliminates noise like braces, explicit returns, and other bits of ceremony that make languages feel cumbersome.

Functional programming with F# makes it possible to write concise, easily testable code that is simpler to parallelize and reason about. However, strict functional styles often require imperative developers to learn new ways of thinking that are not as intuitive. Fortunately, F# makes it possible to incrementally change habits over time. Thanks to its hybrid object-oriented and functional nature, and its clean interoperability with the .net platform, F# developers can gradually shift to a more functional mindset while still using the algorithms and libraries with which they are most familiar.

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F# Programming Essentials Training

F# is excellent for specialties such as scientific computing and data analysis. It is an excellent choice for enterprise development as well. There are a few great reasons why you should consider using F# for your next project.

Concise

F# is not cluttered up with coding noise;  no pesky semicolons, curly brackets, and so on. You almost never have to specify the kind of object you're referencing because of its powerful type inference system. It usually takes fewer lines of code to solve the same issue.

Convenient

Common programming tasks are much easier in F#. These include generating and using state machines, comparison and equality, list processing, as well as complex type definitions. It is very easy to generate powerful and reusable code because functions are first class objects. This is done by creating functions that have other functions as parameters or that combine existing functions to generate a new functionality.

Correctness

F# has a strong type system, and, therefore, prevents many common errors such as null reference exceptions. Valuables are immutable by default which, too, prevents a huge class of errors. You can also encode business logic by utilizing the type system. When done correctly, it is impossible to mix up units of measure or to write incorrect code thereby decresing the need of unit tests.

Concurrency

F# has number of built-in libraries. These libraries help when more than one thing at a time is occurring. Parallelism and asynchronous programming are very simple. There is also a built-in actor model as well as excellent support for event handling and functional reactive programming. Sharing state and avoiding locks are much easier because data structures are immutable by default.

Completeness

F# also supports other styles that are not 100 percent pure. This makes it easier to interact with the non-pure world of databases, websites, other applications, and so on. It is actually designed as a hybrid functional/OO language. F# is also part of the .NET ecosystem. This gives you seamless access to all the third party .NET tools and libraries. It operates on most platforms. These platforms include Linux and smartphones via mono. Visual Studio is integrates with F# as well. This means you get many plug-ins for unit tests, a debugger, a IDE with IntelliSense support, other development tasks. You can use MonoDevelop IDE on Linux.

Related:

F# - Marching Towards Top 10 Programming Languages

What Are the Advantages of Python Over Ruby?

Top 10 Programming Languages Expected To Be In Demand in 2014